The Effect of Induced Hypotension on Intraoperative Blood Loss during Spinal Surgery.
10.4097/kjae.2000.38.6.S6
- Author:
Chang Kil PARK
1
Author Information
1. Department of Anesthesiology, Eulji University School of Medicine, Taejon, Korea.
- Publication Type:Original Article
- Keywords:
Anesthetic technique: induced hypotension;
Hemorrhage: blood loss;
Pharmacology: esmolol;
hydralazine
- MeSH:
Blood Pressure;
Enflurane;
Humans;
Hydralazine;
Hypotension*;
Spinal Fusion
- From:Korean Journal of Anesthesiology
2000;38(6):S6-S12
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: This study was performed to evaluate whether the degree of hypotension influences blood loss during spinal surgery. METHOD: Fifty patients undergoing only one level spinal fusion were assigned to one of three groups. In group 1 (n = 14), the systolic blood pressure (SBP) was maintained at 100 120 mmHg with enflurane. In groups 2 (n = 18) and 3 (n = 18), the SBP were maintained at 80 100 and 60 80 mmHg, respectively. Hydralazine and esmolol were used in the hypotensive groups. RESULTS: Blood losses during operation in groups 2 (554 +/- 287 ml) and 3 (456 +/- 162 ml) were significantly lower than in group 1 (1141 +/- 690 ml) (P < 0.05), although there was no significant difference between groups 2 and 3. The percentage of patients receiving transfusions during the operation in groups 1 and 2 were 57.1 and 5.6%, respectively. CONCLUSIONS: The results show that a moderate reduction in SBP (80 - 100 mmHg) reduces blood loss by more than half in comparison to a mild reduction in SBP (100 - 120 mmHg). However, a severe reduction in SBP (60 - 80 mmHg) does not increase the reduction in blood loss in comparison to moderate hypotension.
