Clinical observation of Fufang-Xuanju capsule combined levofloxacin mesylate tablets in the treatment of chronic epididymitis
10.3760/cma.j.issn.1673-4246.2020.02.005
- VernacularTitle: 复方玄驹胶囊结合甲磺酸左氧氟沙星片治疗慢性附睾炎临床研究
- Author:
Jianwu SHEN
1
;
Liupan KE
1
;
Zhan GAO
1
;
Weijun ZHENG
2
;
Yanyan MOU
2
;
Ran LUO
3
;
Jiasen DING
1
;
Xiaoqin YANG
1
;
Pengxu QIN
1
;
Haote CHEN
1
;
Kuiqing SHAO
1
Author Information
1. Department of Urology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China
2. Basic Medical College, Zhejiang Chinese Medicine University, Hanzhou 310053, China
3. Department of Infertility, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China
- Publication Type:Clinical Trail
- Keywords:
Epididymitis;
Chronic disease;
Fufang-Xuanju capsule;
Pain measurement;
Quality of life;
Comparative effectiveness research
- From:
International Journal of Traditional Chinese Medicine
2020;42(2):120-123
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy of Fufang-Xuanju capsule combined with levofloxacin mesylate tablets in the treatment of chronic epididymitis.
Methods:A total of 76 patients in the Urology Department of Xiyuan Hospital of China Academy of Chinese Medical Sciences who met the inclusion criteria from December 2016 to February 2019, were divided into treatment group (43 cases) and control group (33 cases). The control group was given levofloxacin mesylate tablets orally. The treatment group was given Fufang-Xuanju capsule based on the control group. Both groups were treated for 4 weeks. Chronic epididymitis symptom index (CESI) was used to evaluate the clinical efficacy by pain score and quality of life score.
Results:The total effective rate was 83.7% (36/43) in the treatment group and 63.6% (26/33) in the control group. There was statistically significant difference between the two groups (χ2=4.020, P=0.045). Compared with baseline, the pain scores, quality of life scores and total scores of both groups at 2, 4 weeks after treatment were significantly lower (P<0.01). Two weeks after the treatment, the pain scores, quality of life scores and total scores in the treatment group were significantly lower than those of the control group (F value were 16.132, 9.134 and 23.681, respectively, all Ps<0.01). And 4 weeks after the treatment, the pain scores, quality of life scores and total scores of the treatment group were significantly lower than that of the control group (F value were 28.741, 74.049, 72.483, respectively, all Ps<0.01).
Conclusions:Fufang-Xuanju capsule combined with levofloxacin mesylate tablets can alleviate the pain of patients with chronic epididymitis, improve the quality of life and improve the clinical efficacy.
