Advances in the study of antibodies associated with myasthenia gravis
10.3760/cma.j.issn.1673-4912.2020.02.015
- VernacularTitle: 重症肌无力相关抗体的研究进展
- Author:
Tianqi MA
1
;
Hua WANG
Author Information
1. Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Review
- Keywords:
Antibody;
Myasthenia gravis;
Autoimmune disease;
Thyroid
- From:
Chinese Pediatric Emergency Medicine
2020;27(2):144-148
- CountryChina
- Language:Chinese
-
Abstract:
As an autoimmune disease involving the neuromuscular junction, the pathogenesis of myasthenia gravis(MG) is closely related to autoimmune antibodies.Regarding related antibodies, acetylcholine receptor antibody(AChR-Ab) is the most studied and clear.In recent years, researchers have began to study antibodies other than AChR-Ab due to the presence of AChR-Ab-negative MG patients, such as muscle-specific tyrosine kinase antibodies, low-density lipoprotein 4 antibodies, and explore the corresponding treatment options.This article reviewed the research progress of MG related antibodies, and provided clinical evidence and reference for the future treatment of this disease.
