Comparison of the clinical value of ultrasonic elastography and common ultrasonic features in diagnosing papillary thyroid carcinoma
10.3760/cma.j.issn.1008-6706.2020.02.002
- VernacularTitle: 弹性超声检查技术与常规超声诊断技术对甲状腺乳头状癌的诊断价值比较
- Author:
Yuguo WANG
1
;
Xinping WU
1
;
Xianqin LONG
1
;
Zhihan TAN
1
;
Jing CHEN
1
;
Wenbo DING
1
Author Information
1. Department of Ultrasound, the Integration of Chinese and Western Medicine Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu 210028, China
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Ultrasonography;
Elasticity imaging techniques;
Diagnosis, differential
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(2):134-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical value of ultrasonic elastography (UE) and three common ultrasonic features in diagnosing papillary thyroid carcinoma (PTC).
Methods:From January 2012 to December 2017, the clinical data of 105 cases with PTC which were confirmed by postoperative pathologic examination and 20 cases with benign thyroid nodules (BTN) in the Integration of Chinese and Western Medicine Hospital Affiliated to Nanjing University of Traditional Chinese Medicine were analyzed retrospectively.The UE and common ultrasonic features comprising a taller-than-wide shape, irregular margins and microcalcifications were analyzed.The sensitivity, specificity and area under curve (AUC) of PCT dingnosis with two different ultrasonic parameters are calculated.
Results:Based on surgical pathology, the diagnostic sensitivity of irregular boundary is the highest amony the three paraneters of ordinary ultrasound.Although an irregular margin showed higher sensitivity than taller-than-wide shape and microcalcifications with 71.42% vs.59.04% vs.60.00%, but there was no statistically significant difference (χ2=4.3, P=0.116). There was also no statistically significant difference in specificity (χ2=0.134, P=0.935). The diagnostic efficiency of UE was higher than taller-than-wide shape (Z=3.046, P=0.002), irregular margin(Z=2.962, P=0.003) as well as microcalcifications(Z=3.942, P=0.000), the difference was statistically significant(P<0.05). The diagnostic efficiency of UE was higher than the combined three common ultrasonic features together (Z=3.125, P=0.001).
Conclusion:UE score shows a higher diagnostic efficiency, easy to perform, indicating the important application value in preoperative diagnosis of PTC, and is worthy of promoting in clinic.
