Clinical value of dual phase ASL in evaluation of collateral circulation in patients with severe cerebral vascular stenosis
10.3760/cma.j.issn.1008-6706.2020.02.001
- VernacularTitle: 双时相动脉自旋标记对脑血管重度狭窄患者侧支循环的评估价值
- Author:
Xiaobo LYU
1
;
Xinxin DONG
1
;
Yingdong TAI
2
;
Yongqiang JIA
1
;
Long ZHANG
1
Author Information
1. Department of Imaging, Linfen Central Hospital, Linfen, Shanxi 041000, China
2. Department of Neurology, Linfen Central Hospital, Linfen, Shanxi 041000, China
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Perfusion imaging;
Arterial spin labeling;
Central nervous system vascular malformations;
Collateral circulation;
Cerebrovascular circulation;
Regional blood flow
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(2):129-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical value of dual-phase arterial spin-labeled perfusion imaging(3D-ASL) in the evaluation of collateral circulation compensation in patients with severe cerebrovascular stenosis.
Methods:From December 2017 to August 2018, 73 patients with severe cerebral artery stenosis confirmed by MRA in Linfen Central Hospital were collected and studied.The two-phase superconducting magnetic resonance imaging was performed[Post Label Delay(PLD): 1 525ms, 2 525ms] three-dimensional quasli continuous arterial spin labeling(3D-PCASL) imaging.Bilateral phase cerebral blood flow(CBF) was measured on the affected side and mirror side respectively.The CBF values of the affected side and mirror side were compared and analyzed, and the abnormal perfusion cases were compared and analyzed.
Results:In 73 patients with severe cerebrovascular stenosis, the CBF values of the bilateral affected side[CBF 1 525ms(18.33±6.42)mL·100g-1·min-1, CBF 2 525ms(34.81±11.68)mL·100g-1·min-1] were lower than those of the mirror side[CBF 1 525ms(41.25±16.84)mL·100g-1·min-1, CBF 2 525ms(47.74±14.90)mL·100g-1·min-1], the differences were statistically significant(Z=-9.348, -7.476, all P<0.001). The ratio of abnormal perfusion in PLD=2525ms group[CBF(34.81±11.68)mL·100g-1·min-1]was higher than that in PLD=1 525ms group[CBF(18.33±6.42)mL·100g-1·min-1], the difference was statistically significant(Z=-9.196, P<0.001). The percentage of abnormal perfusion in PLD group of 2 525ms(56.2%) was lower than that in PLD group of 1 525ms(94.5%), the difference was statistically significant(χ2=5.393, P=0.02).
Conclusion:Dual-phase ASL(PLD=1 525ms, 2 525ms) combined with ASL can more accurately evaluate the compensations of fast collateral circulation and slow collateral circulation, and provide individualized treatment.
