Etiology and epidemiological characteristics of gastroenteritis virus in food-borne diarrhea from three cities in Shandong Province, 2017
10.3760/cma.j.issn.0253-9624.2020.02.011
- VernacularTitle: 2017年山东省三个城市食源性腹泻中胃肠炎病毒的病原谱特征分析
- Author:
Wenqiang ZHANG
1
;
Huaning ZHANG
2
,
3
;
Yang HAN
1
;
Xinpeng LI
2
,
3
;
Xiaolin LIU
1
;
Zhongyan FU
1
;
Zhenwang BI
2
,
3
;
Aiqiang XU
1
;
Haiyan WANG
1
Author Information
1. Pathogenic Microorganism Division, Shandong Center for Disease Control and Prevention/Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Jinan 250014, China
2. Institute of Bacterial Infectious Disease Control
3. Shandong Center for Disease Control and Prevention/Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Jinan 250014, China
- Publication Type:Journal Article
- Keywords:
Diarrhea;
Gastroenteritis;
Food-borne diarrhea;
Pathogen spectrum;
Surveillance
- From:
Chinese Journal of Preventive Medicine
2020;54(2):169-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the etiology and epidemiological characteristics of gastroenteritis virus in foodborne diseases from three cities in Shandong.
Methods:From January to December 2017, six sentinel hospitals in Jinan, Yantai and Linyi city of Shandong Province were selected as the research sites. Stool samples of 1 397 diarrhea patients were collected, as well as basic information and clinical symptoms. Duplex quantitative RT-PCR was used to detect Norovirus genogroupⅠ (Nov GⅠ) and genogroupⅡ (Nov GⅡ), Sapovirus (SAV) and Human astrovirus (HAstV), respectively, quantitative RT-PCR was used to detect group A Rotavirus (RVA), and quantitative PCR was used to detect Enteric adenovirus (EAdV). The specific gene of the virus were sequenced and typed. It was compared that the gastroenteritis virus rate in cases with different characteristics and the clinical symptoms difference between the virus positive and negative cases.
Results:The median age (P25, P75) was 23 (1, 42) , mainly male, 57.48% with 803 cased and children under 5 years old, 36.36% with 508 cases. The positive rate of gastroenteritis virus was 33.93% (474 cases), and that of Jinan, Linyi and Yantai City were 32.03% (147/459), 41.54% (189/455) and 28.57% (138/483), respectively (P<0.001). Nov GⅡ had the highest positive rate, 16.54% (231 cases), which, mainly GⅡ.P16/GⅡ.2 (48.28%, 56/116), peaked in May (24.75%, 50/202) and June (19.59%, 38/194). In patients of gastroenteritis virus positive, 44.51% (211/474) had vomiting symptoms, higher than that of patients of gastroenteritis virus negative (34.13%, 315/923). The difference was statistically significant (P<0.001).
Conclusion:In Shandong Province, the majority of gastroenteritis patients were male and children under 5 years old. Nov GⅡ possessed highest epidemic intensity, and peaked in spring and summer. Viral gastroenteritis had atypical clinical symptoms.
