Clinicopathological observation and literature review of cystic meningioangiomatosis
10.3760/cma.j.issn.1006-7876.2020.02.006
- VernacularTitle: 囊性脑膜血管瘤病临床病理观察及文献复习
- Author:
Limeng XIE
1
;
Dehong LU
1
;
Yueshan PIAO
1
;
Xiaotong FAN
2
;
Lianghong TENG
1
;
Shen ZHANG
1
;
Xiuling FU
1
;
Dandan WANG
1
Author Information
1. Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
2. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
- Publication Type:Clinical Trail
- Keywords:
Meningeal neoplasms;
Epilepsy;
Meningioangiomatosis
- From:
Chinese Journal of Neurology
2020;53(2):110-114
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinicopathological features of cystic meningioangiomatosis.
Methods:The clinical manifestations, imaging characteristics and pathological features of a case of cystic meningioangiomatosis were analysed, and the relevant literature was reviewed.
Results:A 16-year-old male patient from Xuanwu Hospital, Capital Medical University had a history of epileptic seizures for more than three months. Magnetic resonance imaging (MRI) demonstrated a cystic mass in the left frontal lobe with long T1 and long T2 signals. Extensive resection of the upper frontal gyrus was performed. The excised lesion presented with a cystic shape after incision and contained colorless translucent liquid. Microscopic examination of the lesion showed that the number of blood vessels in the local cortex of the brain tissue was increased and the vessels appeared to be branching. The blood vessel walls were surrounded by proliferative spindle cells, which were arranged in concentric circles. Immunohistochemical study revealed that those spindle cells and the cyst wall were vimentin positive. These cells had a rich reticular fibers. Ten months after the operation, the general condition of the patient was good, no epileptic seiƶure was observed, and the follow-up MRI did not reveal any residual lesion.
Conclusions:MRI of cystic meningioangiomatosis shows cystic space occupying. Pathological findings show typical features of meningioangiomatosis and cystic space formation. Cystic meningioangiomatosis has good prognosis after surgical resection.
