Progress in the application of novel liquid biopsy techniques in clinical tumor diagnosis and treatment
10.3760/cma.j.issn.1009-9158.2020.03.006
- VernacularTitle: 液体活检新技术在临床肿瘤诊疗中的应用新进展
- Author:
Yanchun WANG
1
;
Renquan LU
;
Lin GUO
Author Information
1. Department of Clinical Laboratory, Fudan University Shanghai Cancer Center Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
- Publication Type:Journal Article
- Keywords:
Liquid biopsy;
Tumor diagnosis and treatment;
Clinical application
- From:
Chinese Journal of Laboratory Medicine
2020;43(2):124-129
- CountryChina
- Language:Chinese
-
Abstract:
Liquid biopsy can non-invasively reveal the status of tumors in vivo, and provides a powerful basis for early diagnosis, personalized treatment monitoring and prognosis prediction. According to the type of tumor-associated material, liquid biopsy covers circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), extracellular vesicles (EVs) and circulating tumor RNA (ctRNA) etc. At present, several liquid biopsy products havebeen approved for clinical use, while many transformation studies have been vigorously carried out. However, there are still many clinical challenges to be solved effectively. Despite the standardization of detection and quality management system of liquid biopsy are lagged with the rapid development of technology, liquid biopsy, as a highly promising detection technology, will become a reliable diagnostic tool with the increasing clinical requirements for facilitating the tumor management.
