Research progress of 6-18Ffluoro-L-dopa PET/CT imaging
10.3760/cma.j.issn.2095-2848.2020.02.012
- VernacularTitle: 18F-DOPA PET/CT显像的研究进展
- Author:
Jingnan WANG
1
,
2
;
Yaping LUO
;
Li HUO
;
Fang LI
Author Information
1. Department of Nuclear Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
2. Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing 100730, China
- Publication Type:Review
- Keywords:
Levodopa;
Fluorine radioisotopes;
Positron-emission tomography;
Tomography, X-ray computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2020;40(2):113-117
- CountryChina
- Language:Chinese
-
Abstract:
6-[18F]fluoro-L-dopa (18F-DOPA) is a levodopa analogue. 18F-DOPA PET/CT imaging is considered as an ideal tool in the diagnosis and evaluation of Parkinson′s disease, brain tumors, pheochromocytoma/paraganglioma, neuroblastoma, gastrointestinal carcinoid, medullary thyroid cancer and congenital hyperinsulinemia. This paper reviews the synthesis, mechanism of localization, imaging procedures, clinical indications and research advances of 18F-DOPA.
