Intracerebral Hemorrhage in Newborn Infants Secondary to Vitamin K Deficiency.
- Author:
Sin JUNG
1
;
Soo Han KIM
;
Sam Suk KANG
Author Information
1. Department of Neurosurgery, Chonnam University Medical School, Kwangju, Korea.
- Publication Type:Original Article
- Keywords:
Coagulation factor;
Intracerebral hemorrhage;
Prothrombin time;
Partial thromboplastin time;
Vitamin K deficiency
- MeSH:
Blood Coagulation Factors;
Cerebral Hemorrhage*;
Hemorrhage;
Humans;
Infant, Newborn*;
Partial Thromboplastin Time;
Prothrombin;
Prothrombin Time;
Thromboplastin;
Vitamin K Deficiency*;
Vitamin K*;
Vitamins*
- From:Journal of Korean Neurosurgical Society
1989;18(1):143-147
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intracerebral hemorrhage secondary to vitamin K deficiency is presented in three newborn infants: 4 days, 28 days and 21 days of age respectively. After the administration of vitamin K(5-10 mg) either intravenously or intramusculary, prolonged prothrombin time(PT) and partial thromboplastin time(PTT) were corrected promptly. Vitamin K dependent coagulation factor deficiency due to vitamin K deficiency is accounted for the pathogenesis of hemorrhage. The possible causes of vitamin K deficiency, diagnostic methods and treatment of this disease entity are reviewed. Neurosurgeons as well as pediatricians should remain alert for the development of intracerebral hemorrhage caused by vitamin K deficiency in neonatal period.
