Research progress on adverse reactions of ketogenic diet

VernacularTitle: 生酮饮食不良反应的研究进展
Author: Mengxiao ZHANG ¹ ; Xiao WEI ¹ ; Shaohong ZHANG ¹ ; Guofang CHEN ¹ ; Chao LIU ¹
Author Information

1. Department of Endocrinology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China
Publication Type:Review
Keywords: Ketogenic diet; Dietotherapy; Side effects
From: Chinese Journal of Endocrinology and Metabolism 2020;36(2):156-160
CountryChina
Language:Chinese
Abstract: Ketogenic diet(KD) has been used for centuries in the treatment of epilepsy, which can restrict calorie and liquid intake, with significant therapeutic effects. In recent years, KD has been proved to have therapeutic effects in other fields, such as obesity, diabetes, hypertension, cancer, Alzheimer′s disease and other chronic diseases. KD has a positive effect on the treatment of many diseases, but the high proportion of fat intake in KD process, as well as too little intake of carbohydrates, proteins and trace elements will lead to a very uneven absorption of nutrients. Therefore, the use of KD to treat disease may cause a variety of adverse reactions, and its long-term results are the subjects of controversy. The purpose of this review is to summarize the literature of KD adverse effects and their prevention and treatment methods, in order to provide guidance and assistance to clinical administration.