Clinical analysis of endovascular repair with covered stent in the treatment of 40 patients with Stanford B type aortic dissection
10.3760/cma.j.issn.1008-6706.2020.01.022
- VernacularTitle: 覆膜支架腔内修复术治疗Stanford B型主动脉夹层40例临床分析
- Author:
Jun CHEN
1
;
Kun LIU
1
;
Kaixin ZHANG
1
Author Information
1. Department of Vascular Surgery, the People's Hospital of Suqian, Nanjing Drum-Tower Hospital Group, Suqian, Jiangsu 223800, China
- Publication Type:Journal Article
- Keywords:
Aneurysm, dissecting;
Stents;
Angioplasty;
Perioperative care;
Intraoperative complications;
Treatment outcome;
Retrospective studies
- From:
Chinese Journal of Primary Medicine and Pharmacy
2020;27(1):90-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of endovascular repair with covered stent in the treatment of Stanford B-type aortic dissection.
Methods:The clinical data of 40 patients with Stanford B-type aortic dissection who underwent endovascular repair with covered stent in the People's Hospital of Suqian, Nanjing Drum-Tower Hospital Group from January 2012 to December 2017 were retrospectively analyzed.The incidence of complications before and after treatment, and its influence on the serum levels of IL-1β, INF-γ, VEGF were analyzed.After one year follow-up, the changes of quality of life score before and after surgery, and the mortality, reoperation or interventional treatment within one year after operation were compared.
Results:Forty patients were successfully implanted with stent grafts, 5 cases of which had a small amount of endoleak, 1 case had postoperative cerebral infarction, and no complications such as paraplegia or renal failure were observed.Compared with before treatment, the serum levels of IL-1β, INF-γ and VEGF were significantly down-regulated after treatment[(3.24±0.19)ng/L vs.(2.02±1.16)ng/L, (2.65±0.23)ng/L vs.(1.14±1.27)ng/L, (1.51±0.17)ng/mL vs.(0.73±0.34)ng/mL], the differences were statistically significant(t=5.037, P=0.001; t=6.071, P=0.000; t=7.314, P=0.000). After 1 year of follow-up, the mortality rate was 5.00%(2/40), and the rate of reoperation or intervention was 5.00%(2/40). The postoperative quality of life(QLQC-30) of the patients was scored in different dimensions: emotional function, body function, role function, cognitive function and social function after 1 month, 6 months and 12 months, the differences were statistically significant(F=6.134, 7.109, 5.134, 6.925, 5.197, all P=0.000).
Conclusion:Endovascular repair with covered stent in the treatment of Stanford B aortic dissection can significantly improve the clinical symptoms of patients, with significant effects and less complications, and can significantly improve patients' survival and quality of life.
