Imaging manifestation of adult bones Langerhans cell histiocytosis
10.3760/cma.j.issn.1673-4904.2020.01.015
- VernacularTitle: 成年人骨骼朗格汉斯细胞组织细胞增生症的影像学表现
- Author:
Lezhen HUANG
1
;
Wangmei JIANG
2
;
Qiande QIU
3
Author Information
1. Department of Radiology, Yueqing Sixth People′s Hospital of Zhejiang Province, Zhejiang Yueqing 326503, China
2. Department of Radiology, Yueqing Third People′s Hospital of Zhejiang Province, Zhejiang Yueqing 325604, China
3. Department of Radiology, Wenzhou People′s Hospital of Zhejiang Province, Zhejiang Wenzhou 325000, China
- Publication Type:Journal Article
- Keywords:
Histiocytosis, Langerhans-cell;
Adult;
Disease attributes;
Retrospective studies
- From:
Chinese Journal of Postgraduates of Medicine
2020;43(1):61-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the imaging features of adult bones Langerhans cell histiocytosis (LCH).
Methods:The DR, CT, and MRI findings of 25 adults patients with LCH from January 2008 to June 2019 in Yueqing Sixth People′s Hospital of Zhejiang Province (3 cases), Yueqing Third People′s Hospital of Zhejiang Province (7 cases) and Wenzhou People′s Hospital of Zhejiang Province (15 cases) were retrospectively analyzed.
Results:Among the 25 patients, the lesions located in the skull in 5 cases, in the spine in 5 cases, in the long bones in 10 cases, in the other flat bones in 3 cases, and in multiple bones in 2 cases. DR features (17 cases) showed: cystic destruction in 11 cases (6 cases with dilated changes), osteolytic damage in 6 cases; peripheral bone cortex thickening in 5 cases, bone lesions with less smooth inner edge in 4 cases, soft tissue mass around the lesion in 12 cases; 'hole set cave sign' in 2 cases, 'flat vertebra' in 2 cases, and 'button-like dead bone' in 1 case. CT features (15 cases) showed: cystic destruction in 9 cases (5 cases with dilated changes), osteolytic damage in 6 cases; 'hole set cave sign' in 2 cases, 'flat vertebra' in 2 cases, and 'button-like dead bone' in 1 case. MRI features (14 cases) showed: cystic destruction in 9 cases (5 cases with dilated changes), osteolytic damage in 5 cases; in the bone destruction area, 8 cases had low T1WI signal and high T2WI signal, 4 cases had equal T1WI signal and higher mixed T2WI signal, 2 cases had slightly higher T1WI signal and higher mixed T2WI signal; STIR lipoprotein sequence showed high signal in 11 cases, and isointense signal in 3 cases; DWI showed high signal.
Conclusions:The imaging performance of adults LCH has certain characteristics, and the diagnostic accuracy can be improved according to the imaging performance and the clinic.
