Research progress of the factors affecting human papillomavirus clearance after CINⅢ hysterectomy

VernacularTitle: 宫颈上皮内瘤变Ⅲ级子宫全切术后影响人乳头瘤病毒清除相关因素的研究进展
Author: Xing LI ¹ ; Yile CHEN ; Mulan LIAO ; Wang FENG ; Ting LIANG
Author Information

1. Department of Gynecologic Oncology, Hunan Cancer Hospital, Changsha 410000, China
Publication Type:Review
Keywords: Cervical intraepithelial neoplasia; Hysterectomy; Human papillomavirus; Review
From: Journal of Chinese Physician 2020;22(1):151-154
CountryChina
Language:Chinese
Abstract: Total hysterectomy is a treatment for cervical intraepithelial neoplasia Ⅲ (CINⅢ), and its recurrence rate is very small. In recent years, with the development of colposcopy and the increase of postoperative follow-up rate, the detection rate of vaginal intraepithelial neoplasia (VAIN) and vaginal cancer after CINⅢ hysterectomy has increased significantly. In recent years, a number of studies have found that persistent human papillomavirus (HPV) infection is the most important factor leading to the recurrence of vaginal stump after CINⅢ level hysterectomy, so eliminating HPV infection can improve the patient's performance. The prognosis of persistent HPV infection is affected by many factors. The author reviewed the factors related to the clearance of HPV after CINⅢ hysterectomy. The purpose of this study is to provide a theoretical basis for improving the prognosis of patients and delaying the recurrence time after CINⅢ hysterectomy.