Advances in the study of urinary exosomes as biomarkers of genitourinary tumors
10.3760/cma.j.issn.1000-6702.2020.01.018
- VernacularTitle: 尿液外泌体作为泌尿系统肿瘤分子标志物的研究进展
- Author:
Yalong XU
1
;
Xi CHEN
;
Jin JI
;
Fubo WANG
Author Information
1. Department of Urology, Shanghai Changhai Hosipital, Shanghai 200433, China
- Publication Type:Review
- Keywords:
Urine;
Exosome;
Genitourinary tumors;
Biomarkers;
Diagnosis;
Prognosis
- From:
Chinese Journal of Urology
2020;41(1):72-75
- CountryChina
- Language:Chinese
-
Abstract:
Exosomes are membranous vesicles secreted by a variety of cells, including tumor cells, with stable characters, which can reflect the physiological/pathological state of the source cells, indicating good sources of biomarkers for early diagnosis and prognosis of tumors. Urine exosomes are directly derived from the urinary system and play a more direct role in the diagnosis and prognosis of urinary system tumors. This paper reviews the recent advances in urinary exosomes as molecular markers for the early diagnosis of genitourinary tumors.