Reserch advances in the application of exosome in wound healing
10.3760/cma.j.issn.1009-4598.2020.01.021
- VernacularTitle: 外泌体应用于创面修复的研究进展
- Author:
Chen ZHANG
1
;
Hongsen BI
;
Zhenmin ZHAO
;
Fangfei NIE
Author Information
1. Department of Plastic Surgery, Peking University Third Hospital, Beijing 100191, China
- Publication Type:Review
- Keywords:
Exosome;
Wound healing;
Tissue repairing
- From:
Chinese Journal of Plastic Surgery
2020;36(1):94-98
- CountryChina
- Language:Chinese
-
Abstract:
Exosome is a double-layer membrane vesicle secreted by several kinds of cells. Exosome is major way of cell paracrine activity with a wide range of sources and high security feature. This paper reviews recent progress of exosomes in promoting wound healing. Studies have shown that exosomes can be applied to wound treatment by immune regulation, regulating fibroblast activity, promoting angiogenesis, inhibiting scar formation and other mechanisms. Compared with traditional stem cell therapy, exosomes have better applied prospect in clinical practise.
