Prognosis and risk factors of tricuspid regurgitation after transcatheter closure of perimembranous ventricular septal defects in children
10.3760/cma.j.issn.2095-428X.2020.01.012
- VernacularTitle: 儿童经导管介入封堵膜周部室间隔缺损术后三尖瓣反流的预后及影响因素
- Author:
Yunxia DENG
1
;
Wenchuo ZHAO
2
;
Lijun FU
2
;
Jie SHEN
2
;
Yiwei CHEN
2
;
Wei JI
2
;
Diqi ZHU
2
;
Fen LI
2
Author Information
1. Department of Cardiology, Chengdu Women and Children′s Central Hospital, Women and Children′s Hospital Affiliated to School of Medicine, University of Electronic Science and Technology of China, Chengdu 611731, China
2. Department of Cardiology, Shanghai Children′s Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
- Publication Type:Journal Article
- Keywords:
Ventricular septal defects;
Tricuspid regurgitation;
Septal occlude device;
Retrospective study
- From:
Chinese Journal of Applied Clinical Pediatrics
2020;35(1):46-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the incidence and prognosis of tricuspid regurgitation after transcatheter closure of perimembranous ventricular septal defects in pediatric patients as well as the risk factors of regurgitation occurrence or aggravation.
Methods:Clinical data of 1 108 patients who underwent percutaneous closure in Shanghai Children′s Medical Center, School of Medicine, Shanghai Jiaotong University from January 2011 to January 2017 was analyzed retrospectively, and the prognosis and risk factors of postoperative tricuspid regurgitation and aggravation were also analyzed.
Results:Mild tricuspid regurgitation occurred in 24 cases after surgery with the incidence of 2.1%.Among 5 cases with mild or above preoperative tricuspid regurgitation, the regurgitation was alleviated after surgery in 4 cases.No severe tricuspid regurgitation requiring surgical intervention occurred in any patient during follow-up.Univariate analysis showed that intervention time (P<0.05) and residual shunt (P<0.05) were risk factors for mild or above tricuspid regurgitation after intervention.Binary regression analysis indicated that the size of the occluder (mm) (OR=1.48, 95%CI: 1.13-1.90) and residual shunt (OR=6.53, 95%CI: 1.69-25.30) were risk factors for tricuspid regurgitation after intervention (all P<0.05).
Conclusions:There is a certain incidence of tricuspid regurgitation after transcatheter closure of perimembranous ventricular septal defects, but most tricuspid regurgitation do not need surgical intervention.The intervention time, size of occluder and residual shunt are risk factors of intraoperatively or postoperatively tricuspid regurgitation.
