Research progress in exosomes delivery in the jaw regeneration
10.3760/cma.j.issn.1002-0098.2020.01.013
- VernacularTitle: 外泌体运输调控颌骨再生的研究进展
- Author:
Xiaoxuan ZHANG
1
;
Xing WANG
Author Information
1. Department of Oral and Maxillofacial Surgery, Shanxi Medical University School and Hospital of Stomatology, Taiyuan 030001, China
- Publication Type:Review
- Keywords:
Exosomes;
Bone regeneration;
Jaw;
Bone marrow mesenchymal stem cells
- From:Chinese Journal of Stomatology
2020;55(1):62-66
- CountryChina
- Language:Chinese
-
Abstract:
Large area defect of jaw caused by trauma, tumor resection, congenital malformation and periodontitis is a critial situation for oral and craniofacial reconstruction. Recent studies have shown that some exosomes carrying specific biological information play a role in promoting tissue regeneration. Compared to allogeneic stem-cell transplantation, exosomes have lower immunogenicity, and can facilitate storage and quantitative use, thus have great potential in tissue engineering. This article reviewed the regeneration process of jaw bone and the regulatory effect of exosomes transport on bone regeneration, as well as the research progress of exosomes in jaw bone-related diseases.
