A Case of Secondary Pulmonary Alveolar Proteinosis Accompanied by Acute Erythroleukemia.
- Author:
Young Woong WHANG
;
Byung Hyun CHOI
;
Nae Hee LEE
;
Suck Ho KWON
;
Jeong Il JEONG
;
Jae Who PARK
;
Hee Sun JON
;
Kyung Joo PARK
;
Kwang Hwa PARK
;
Kang Yong LEE
;
Hugh Chul KIM
- Publication Type:Case Report
- Keywords:
Secondary alveolar proteinosis;
Acute erythroleukemia
- MeSH:
Biopsy;
Bone Marrow;
Cough;
Drug Therapy;
Eosinophils;
Humans;
Leukemia, Erythroblastic, Acute*;
Lung;
Male;
Pneumonia;
Pulmonary Alveolar Proteinosis*;
Radiography, Thoracic;
Rare Diseases;
Respiratory Sounds;
Tomography, X-Ray Computed
- From:Korean Journal of Medicine
1997;53(1):128-132
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pulmonary alveolar proteinosis is a rare disease, which hallmark is a dense accumulation of PAS positive phospholipid material within alveolar sac. Pulmonary alveolar proteinosis is classified as primary form of unknown etiology and secondary form associated with other diseases. We report a case of secondary pulmonary alveolar proteinosis associated with acute erythroleukemia. A C year old male patient complained of nonproductive cough and general weakness, and presented fine inspiratory crackles at both lower lung field. Chest radiographs and high resolution CT scans showd a lobular pattern of ground-grass opacity with interlobular septal thickening in the center field of the both lungs, Bone marrow aspiration and biopsy revealed acute erythroleukemia. Open lung biopsy revealed PAS positive eosinophilic granular material filled in alveoli. He was treated with TAD chemotherapy, but died from multiorgan failure with pneumonia 22days after chemotherapy.
