The pathogenesis and antioxidant treatment of age-related macular degeneration

VernacularTitle:年龄相关性黄斑变性的发病机制与抗氧化治疗
Author: Zi-Wen Sun ^{1
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Author Information

1. Department of Ophthalmology, Fourth Affiliated Hospital of Kunming Medical University(the Second People'
2. s Hospital of Yunnan Province)
3. Yunnan Eye Institute
4. the Ocular Disease and Clinical Medicine Research Center of Yunnan Province
5. the Ocular Disease Clinical Medicine Center of Yunnan Province
6. Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology
7. Expert Workstation of Yao Ke, Kunming 650021, Yunnan Province, China
Publication Type:Journal Article
Keywords: age-related macular degeneration; senility; oxidative stress; antioxidant; pigment
From: International Eye Science 2020;20(3):468-471
CountryChina
Language:Chinese
Abstract: Aged-related macular degeneration(ARMD)is prone to occur in the people who aged 50a or older. The disease can lead to partial or even complete loss of sight in single or both eyes progressively. The pathogenesis of ARMD is still unclear, but the previous studies have shown that oxidative stress plays an important role. The mechanism of antioxidants on ARMD has gradually become a hotspot in recent years. In this paper, we briefly reviewed the mechanism of ARMD caused by oxidative stress and the application of antioxidants on ARMD.