Research progress on cell signal transduction pathway mediating age-related cataract
10.3980/j.issn.1672-5123.2020.3.02
- VernacularTitle:细胞信号转导通路介导年龄相关性白内障发生的研究进展
- Author:
Zhong-Ying Wang
1
Author Information
1. 1Mudanjiang Medical College, Mudanjiang 157011, Heilongjiang Province, China2Department of Genetics, National Research Institute for Family Planning, Health Department, Beijing 100081, China3Department of Ophthalmology, Hongqi Hospital of Mudanjiang Medical College, Mudanjiang 157011, Heilongjiang Province, ChinaCo-first authors: Zhong-Ying Wang and Dong-Mei Su
- Publication Type:Journal Article
- Keywords:
age-related cataract;
apoptosis;
signal transduction
- From:
International Eye Science
2020;20(3):404-409
- CountryChina
- Language:Chinese
-
Abstract:
Age-related cataract is a blinding eye disease that affects vision due to opacity of intraocular lens, ranking first in the world. Under oxidative stress, the activation of apoptosis related signal transduction pathways in lens epithelial cells is the main mechanism mediating age-related cataract. There are many related signaling pathways for apoptosis, and it is a complex network system. The purpose of this literature review is to summarize different apoptotic cell signal transduction pathways that mediate age-related cataract, laying the foundation for further researching.
- Full text:202003002.pdf
