CT-DRAGON score predicts outcome after endovascular treatment in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2019.09.005
- VernacularTitle: CT-DRAGON评分预测急性缺血性卒中患者经血管内治疗后转归
- Author:
Yang ZHANG
1
;
Qingfang MA
2
;
Xinmin FU
1
;
Junjie LU
1
;
Qingqing ZHANG
1
;
Guofang CHEN
1
;
Lei PING
1
Author Information
1. Department of Neurology, Xuzhou Central Hospital, Xuzhou 221009, China
2. Department of Neurosurgery, Xuzhou Central Hospital, Xuzhou 221009, China
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain ischemia;
Tomography, X-ray computed;
Thrombectomy;
Endovascular procedures;
Stents;
Thrombolytic therapy;
Treatment outcome
- From:
International Journal of Cerebrovascular Diseases
2019;27(9):662-667
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of CT-DRAGON score for clinical outcomes after endovascular treatment in patients with acute ischemic stroke.
Methods:Patients with acute ischemic stroke underwent endovascular intervention in Xuzhou Central Hospital from May 2015 to June 2019 were enrolled retrospectively. CT-DRAGON score was performed before treatment, and the outcomes of patients were evaluated by the modified Rankin Scale (mRS) at 3 months after treatment, and good outcome was defined as mRS0-2. Multivariate logistic regression analysis was used to determine the independent factors for the outcomes. The receiver operating characteristic (ROC) curve was used to analyze the predictive value of CT-DRAGON score for clinical outcome.
Results:A total of 67 patients were enrolled. The age was 68.69±11.63 years. The median CT-DRAGON score was 5 (interquartile interval: 4-7), and the baseline NIHSS score was 17.45±5.19. Thirty-five patients (52.2%) had a good outcome and 32 (47.8%) had a poor outcome, of which 13 (19.4%) died. Multivariate logistic regression analysis showed that higher CT-DRAGON score was an independent predictor for poor outcome (odds ratio 1.997, 95% confidence interval 1.271-3.136; P=0.003). The ROC curve analysis showed that the area under the curve of CT-DRAGON score to clinical outcome was 0.808 (95% confidence interval 0.706-0.911; P<0.001). The optimal cutoff value was 5, the corresponding sensitivity was 65.6%, and the specificity was 80.0%.
Conclusions:Baseline CT-DRAGON score can effectively predict the clinical outcome of patients with acute ischemic stroke at 3 months after endovascular treatment.
