Risk factor analysis of early complications after pancreaticoduodenectomy
10.3760/cma.j.issn.1673-4203.2019.09.013
- VernacularTitle: 胰十二指肠切除术后早期并发症的影响因素分析
- Author:
Likun WANG
1
;
Ming KUANG
2
;
Yunpeng HUA
2
;
Bin CHEN
2
;
Qiang HE
2
;
Qian WANG
2
;
Lijian LIANG
2
;
Baogang PENG
2
Author Information
1. Department of General Surgery, Fourth Affiliated Hospital of Anhui Medical University, Hefei 230012, China
2. Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
- Publication Type:Journal Article
- Keywords:
Pancreatoduodenectomy;
Postoperative complications;
Risk factor;
Mortality
- From:
International Journal of Surgery
2019;46(9):626-630
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyse of risk factors for early complications after pancreaticoduodenectomy.
Methods:Retrospective analysis of 280 cases of pancreaticoduodenectomy in the First Affiliated Hospital, Sun Yat-sen University from January 1999 to October 2009, including 175 males and 105 females; the average age was 57 years, the range is 19 to 81 years old. Observe the perioperative condition and postoperative complications of the patient. Logistic regression analysis was used to analyze risk factors associated with early postoperative complications.
Results:Among the 280 patients, 81.1% had preoperative jaundice with obstructive jaundice, the median operation time was 5.5 h. the intraoperative blood loss was (558.0±35.0) ml, 16 patients underwent multiple organ resection. The total postoperative complications was 31.1%. Common postoperative complications were abdominal infection/abscess (10.4%), hemorrhage (7.1%), and pancreatic fistula (2.1%). The pancreaticoenterostomy was mainly performed with a nested end-to-end anastomosis (87.1%) and a bundled pancreaticojejunostomy (7.9%). Logistic regression analysis showed that age, comorbidity, jaundice, preoperative yellowing, pancreatic texture, pancreatic duct placement, prophylactic application of somatostatin, combined organ resection and pancreaticojejunostomy were not predictor of major postoperative complications.
Conclusions:The incidence of early abdominal complication after pancreaticoduodenectomy is high. There is no significant correlation between the common risk factors in perioperative period and the occurrence of serious complications in the early postoperative period.
