Research progress on the relationship between autism and intestinal microbiota

VernacularTitle: 孤独症谱系障碍与肠道微生物研究进展
Author: Yaojing LI ¹ ; Shunying YU
Author Information

1. Shanghai Mental Health Center, Shanghai JiaoTong University School of Medicine, Shanghai 200030, China
Publication Type:Review
Keywords: Autism spectrum disorder; Intestinal microbiota; Microbiome-gut-brain axis
From: International Journal of Pediatrics 2019;46(9):644-647
CountryChina
Language:Chinese
Abstract: There are trillions of microbes in human gut, which are related to health and diseases closely.In recent years, with the popularization of the concept of microbiome-gut-brain axis, the influence of intestinal microbiota on central nervous system diseases has drawn increasing attention.Gastrointestinal symptoms are common in children with autism spectrum disorder(ASD), and some studies have also indicated that correcting the dysbiosis of gut microbiome can not only improve the gastrointestinal problems, but also alleviate the symptoms of autism to some extent.Therefore, the relationship between intestinal microbes and ASD has attracted researchers′ attention.This review focuses on several kinds of gut microbesmicrotes that have been extensively studied to reveal the relationship between the microbesmicrotes and autism spectrum disorders and their potential pathogenic or protective mechanisms.