The classification, prognosis and causes of acute gastrointestinal injury in PICU children
10.3760/cma.j.issn.1673-4912.2019.09.008
- VernacularTitle: PICU儿童急性胃肠损伤的分级、预后及原因探讨
- Author:
Tufeng LI
1
;
Yuge HUANG
;
Mianling ZHONG
;
Miaofen LI
Author Information
1. Guangdong Medical University, Zhanjiang 524000, China
- Publication Type:Journal Article
- Keywords:
Children;
Acute gastrointestinal injury;
Prognosis;
Pediatric critical illness score
- From:
Chinese Pediatric Emergency Medicine
2019;26(9):676-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the classification, prognosis and causes of acute gastrointestinal injury(AGI) in PICU patients in our hospital.
Methods:Patients were included if they had been hospitalized in PICU at least 24 h before the AGI diagnosis from January 2015 to April 2018.Patients were classified according to severity of gastrointestinal dysfunction.Clinical characteristics, pediatric critical illness scores, pediatric logistic organ dysfunction score 2 and 28-day mortality, as well as mechanical ventilation were recorded.
Results:A total of 220 patients were enrolled.AGIⅠ-Ⅳ groups included 66(30.0%), 97(44.1%), 37(16.8%)and 20(9.1%) patients, respectively, while primary AGI and secondary AGI included 149(67.7%) and 71 (32.3%)patients, respectively.There was no significant difference among four groups in gender, hospitalization time in PICU and total hospitalization time (P>0.05), but there were significant differences in median age, pediatric critical illness scores, pediatric logistic organ dysfunction score 2 and proportion of mechanical ventilation(P<0.05). Median age(month) was 3 (1, 15), 11 (2, 24), 11 (2, 36), and 4 (0.5, 11.5), respectively in AGI Ⅰ-Ⅳ groups.The total 28-day mortality rate of AGI Ⅰ-Ⅳ groups accounted for 0, 0, 13.2% and 3.2%, respectively.
Conclusion:Patients in PICU are prone to AGI.AGIⅠand AGI Ⅱare common.The prognosis is associated with classification of AGI.The higher grades of AGI are, the worse prognosis is.The prognosis of AGI Ⅲ is the worst, because of different causes.
