Determination and analysis of allergen specific IgE in 1 028 children with allergic dermatosis
10.3760/cma.j.issn.1008-1372.2019.09.017
- VernacularTitle: 1 028例过敏性皮肤病患儿过敏原特异性IgE测定及分析
- Author:
Yuyang HAN
1
;
Lixia BAI
2
;
Yuanjun LI
1
;
Hui XUE
1
;
Xinglian ZHANG
1
;
Xiaoying YANG
1
Author Information
1. Department of Dermatology, Children′s Hospital of Shanxi Province, Taiyuan 030013, China
2. Department of Infection Management, Children′s Hospital of Shanxi Province, Taiyuan 030013, China
- Publication Type:Journal Article
- Keywords:
Anaphylaxis;
Allergens;
Immunoglobulin E;
Child
- From:
Journal of Chinese Physician
2019;21(9):1359-1362
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the differences in specific IgE of allergic diseases.
Methods:The allergens in 1 028 patients (including 606 cases of eczema/specific dermatitis, 319 Cases of urticaria, 103 cases of papular urticaria and prurigo) were detected by German Allergy Screen Immune mark method.
Results:There were statistically significant differences (P<0.05) in the positive rate of allergens among the four allergic diseases, including Penicillium notatum/ Piptocephalis/ aspergillus fumigatus/aspergillus niger/Alternaria (χ2=6.663), milk (χ2=10.320) and cashew nut (χ2=14.325); The common allergen in <1-year-old group was cat dander (22.75%), egg white (35.93%); The common allergen in 1 to 3 years old group was dog dander (22.17%), milk (61.82%) and crab (3.45%). The common allergen in>3-year-old group was dust mite (10.77%), cockroach (3.52%), Penicillium notatum/Piptocephalis/ aspergillus fumigatus/aspergillus niger/Alternaria (21.32%), Short ragweed/artemisia/Humulus scandens/quinoa (14.73%). The positive rate of specific IgE against house dust in the third quarter was the highest (17.78%) and the difference was statistically significant (χ2=14.443, P=0.002). Among the statistically significant difference in the positive rate of specific IgE between eczema/atopic dermatitis in different age groups (χ2=10.204, P=0.006), the positive rate in the group of 1 to 3 years was the highest.
Conclusions:Different diseases, ages, and seasonal specific allergens are different, individualized treatment can be carried out according to disease types, ages and seasons.
