The value of contrast-enhanced ultrasonography in differential diagnosis of orbit tumors in extraconal compartment
10.3760/cma.j.issn.1004-4477.2019.09.012
- VernacularTitle: 超声造影定量参数对眼眶肌锥外间隙良恶性肿瘤的鉴别价值
- Author:
Yao ZHANG
1
;
Wenwei CHEN
;
Wei HU
;
Bin SUN
;
Qing DENG
;
Xin HUANG
;
Xingyue HUANG
;
Jun ZHANG
;
Shang WANG
Author Information
1. Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Clinical Trail
- Keywords:
Contrast-enhanced ultrasonography;
Orbit tumors in extraconal compartment;
Time-intensity curve;
Dynamic vascular pattern
- From:
Chinese Journal of Ultrasonography
2019;28(9):798-802
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide a reference for differential diagnosis of orbit tumors in extraconal compartment by analyzing the parameters of contrast-enhanced ultrasonography (CEUS).
Methods:A total of 76 patients with orbit tumors in extraconal compartment who underwent CEUS examination were retrospectively analyzed. These patients were divided into two groups depending on histological diagnosis including 27 cases with malignant tumor and 49 cases with benign tumor. CEUS images were analyzed using Sonoliver software. The time-intensity curve (TIC) and dynamic vascular pattern curve (DVPC) were acquired and the characteristics of the arterial flow infusion of these were analyzed. The related parameters such as time of arrival time(AT), rise time (RT), time to peak(TTP), mean transit time(mTT), slope of rise(K1), the absolute value for slope of down (K2) were also obtained. The differences of DVPC, TIC and quantitative parameters between the two groups were compared. Receiver operating curve analysis was used to acquire the cut-off values of these parameters for differential diagnosis.
Results:①TICs of the benign tumors were mainly fast rise and slow drop and DVPCs were mainly positive biphasic, while TICs of the malignant tumors were mainly fast rise and fast drop and DVPCs were mainly biphasic. ②The differences of quantitative parameters IMAX, K1, K2, mTT and RT of TICs were statistically significant between the two groups (P<0.05), while those of AT and TTP were not (P>0.05). ③IMAX=456.2%, K1=109.6, K2=35.2, RT=7.9 s, mTT=28.1 s were the best cut-off values for differential diagnosis. Among these parameters, mTT with 28.1 s had the highest diagnostic value(sensitivity: 81%, specificity: 77%).
Conclusions:The quantitative CEUS parameters can provide effective reference for differential diagnosis of orbit tumors in extraconal compartment.
