The value of contrast enhanced ultrasound in breast cancer biopsy
10.3760/cma.j.issn.1004-4477.2019.09.009
- VernacularTitle: 超声造影在指导乳腺癌穿刺活检中的价值
- Author:
Lili XI
1
;
Yaqing CHEN
1
;
Jun JIANG
1
;
Yunkai ZHU
1
;
Wenbin GUAN
2
;
Yuehong QU
1
;
Lifeng WANG
2
Author Information
1. Department of Ultrasound in Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
2. Department of Pathology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
- Publication Type:Clinical Trail
- Keywords:
Contrast enhanced ultrasound;
Breast neoplasms;
Biopsy, needle
- From:
Chinese Journal of Ultrasonography
2019;28(9):782-786
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively investigate the value of contrast enhanced ultrasound (CEUS) in breast cancer biopsy.
Methods:A total of 49 consecutive patients with biopsy confirmed breast cancer were retrospectively analyzed. All patients underwent CEUS and biopsies were thus performed targeting both the high perfusion and low/non-perfusion regions on CEUS. The diagnostic performance and core cancer involvement of the biopsy cores taken from the high perfusion regions were compared with those from the low/non-perfusion.
Results:A total of 53 breast cancer lesions were biopsy confirmed in 49 patients.CEUS revealed homogeneous enhancement in 8 lesions (15.1%), and heterogeneous enhancement in 45 lesions (84.9%). The diagnostic accuracy rate for biopsy cores taken from the high perfusion regions was significantly higher than that from the low/non-perfusion regions (98.5% vs 72.9%, P<0.01). The core cancer involvement was also higher in high perfusion lesions (55% vs 30%, P<0.01).
Conclusions:CEUS can differentiate the active area and necrotic fibrosis area of breast tumors by displaying the microvessels, thus contributing to the selection of biopsy sites.
