Analysis of influencing factors on hepatic encephalopathy in patients with non-cirrhotic portal hypertension
10.3760/cma.j.issn.1007-3418.2019.09.003
- VernacularTitle: 非肝硬化门静脉高压患者肝性脑病影响因素分析
- Author:
Min LIU
1
;
Wentao HE
2
;
Dongsheng CHEN
3
;
Dehai HU
3
Author Information
1. Department of Pharmacy, the First People's Hospital of Lianyungang, Jiangsu Province 222002, China
2. Department of Infectious Diseases, the Fourth People's Hospital of Lianyungang, Jiangsu Province 222002, China
3. Department of Infectious Diseases, the First People's Hospital of Lianyungang, Jiangsu Province 222002, China
- Publication Type:Journal Article
- Keywords:
Hepatic encephalopathy;
Infection;
Non-cirrhotic portal hypertension;
Upper gastrointestinal bleeding;
Portal-systemic shunt
- From:
Chinese Journal of Hepatology
2019;27(9):673-676
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the incidence of hepatic encephalopathy (HE) in patients with non-cirrhotic portal hypertension (NCPH) and to explore its risk factors.
Methods:The incidence rate of HE in 150 cases with NCPH was evaluated in two hospitals, and 188 cases of compensated cirrhosis patients were taken as control. Logistic regression was used to screen for independent risk factors for HE in patients with NCPH.
Results:The incidence of overt hepatic encephalopathy (OHE) in patients with NCPH was not statistically significantly different from that in patients with cirrhosis (4.7% vs. 6.9%, P = 0.682). The incidence of mild hepatic encephalopathy (MHE) was significantly lower than that of cirrhosis patients (32.7% vs. 46.3%, P < 0.05). The presence of upper gastrointestinal bleeding, infection and portosystemic venous shunt were the main independent factors for HE in NCPH patients (OR > 1, P < 0.05).
Conclusion:HE is one of the important complications of NCP, and may be influenced by factors such as upper gastrointestinal bleeding, infection and portosystemic venous shunt.
