Research progress on the risk factors, prevention and therapy in posthepatectomy liver failure
10.3760/cma.j.issn.1007-8118.2019.09.020
- VernacularTitle: 肝切除术后肝功能衰竭危险因素与防治的研究进展
- Author:
Yongchao ZENG
1
;
Hongda DING
;
Ruoyao ZOU
;
Yang SU
Author Information
1. Department of Hepatobiliary-Splenic Surgery, Shengjing Hospital of China Medical University, Shenyang 110000, China
- Publication Type:Review
- Keywords:
Liver failure;
Hepatectomy;
Risk factors;
Therapy
- From:
Chinese Journal of Hepatobiliary Surgery
2019;25(9):711-715
- CountryChina
- Language:Chinese
-
Abstract:
The prevention and treatment of posthepatectomy liver failure (PHLF) is a difficult problem for hepatectomy. PHLF is characterized by many risk factors, limited treatment methods and high mortality. There are many factors that lead to the insufficient quantity or quality of postoperative remnant liver cells, such as the comorbid conditions of patients, underlying disease of the liver, excessive liver resection and so on, which are increase the incidence of PHLF. However, the therapeutic treatment of PHLF is limited at present, the key to reduce the morbidity and mortality of PHLF lies in the accurate evaluation and screening of high-risk patients. This paper reviewed the relevant literature on the definition, risk factors and clinical prevention and treatment of posthepatectomy liver failure.