Recent advances in the relationship between cerebral small vessel disease and hemorrhagic transformation after intravenous thrombolysis in acute ischemic stroke
10.3760/cma.j.issn.1006-7876.2019.09.014
- VernacularTitle: 脑小血管病与急性缺血性卒中静脉溶栓后出血性转化的关系研究进展
- Author:
Shiyu ZHANG
1
;
Li TIAN
2
;
Jinwei LI
1
;
Weiyu TENG
1
Author Information
1. Department of Neurology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China
2. Department of Gerontology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China
- Publication Type:Review
- Keywords:
Cerebral small vessel disease;
Stroke;
Intravenous thrombolysis;
Hemorrhagic transformation
- From:
Chinese Journal of Neurology
2019;52(9):776-780
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease refers to a series of clinical, imaging and pathological syndromes caused by various diseases affecting small arteries, arterioles, capillaries, venules, and venules in the brain, thereby causing ischemia or hemorrhage in brain tissue. At present, intravenous thrombolytic therapy is the first choice for the treatment of acute ischemic stroke, however a large number of studies have shown that the presence of cerebral small vessel disease before acute ischemic stroke increases the risk of intravenous thrombolysis. In this article, the recent research progresses about the relationship between cerebral small vessel disease and hemorrhagic transformation after venous thrombolysis in acute ischemic stroke are reviewed, aiming to provide a new reference for clinical intravenous thrombolytic therapy.
