Whole body vibration combined with botulinum neurotoxin A injection in the treatment of spastic diplegic cerebral palsy
10.3760/cma.j.issn.0254-1424.2019.09.012
- VernacularTitle: 全身振动训练联合肉毒毒素注射对痉挛型双瘫脑瘫儿童尖足及粗大运动功能的影响
- Author:
Xuesong REN
1
;
Zhijun CAI
1
;
Xiaoan ZHANG
2
;
Jie LIU
1
;
Zhen CHEN
1
;
Dengna ZHU
1
Author Information
1. Department of Children′s Rehabilitation, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China
2. Department of Imaging, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China
- Publication Type:Clinical Trail
- Keywords:
Cerebral palsy;
Whole body vibration;
Botulinum neurotoxin A;
Tipped foot;
Gross motor function
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(9):688-692
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of combining whole body vibration with botulinum neurotoxin A injections on tiptoe and the gross motor function of children with spastic diplegic cerebral palsy.
Methods:Sixty spastic diplegic children with tipped foot aged between 2 to 5 were equally divided into a control group and an experimental group randomly. The control group received 3 IU/kg botulinum neurotoxin A injections to the medial and lateral heads of the gastrocnemius muscle. Then 5 daily courses of conventional training were administered 5 days a week for 3 weeks beginning 24 hours after the injections. The experimental group additionally received 2min of whole body vibration 3 or 4 times per day with one-minute rests, 5 days per week for 5 weeks. All of the children were assessed before the experiment and 1, 3 and 6 months later using the modified Tardieu scale (MTS) and the R1 and R2 ankle and dimensions D and E of the gross motor function measurement scale (GMFM-88).
Results:There were no significant differences between the two groups before the treatment. Afterward, the average MTS, R1, R2 and GMFM-88 scores of both groups were significantly improved. The average MTS, R1 and R2 scores of the experimental group after treatment were significantly better than the control group′s averages. The average GMFM-88 score of the experimental group was not significantly different from that of the control group after 1 month, but after 3 and 6 months significant differences emerged.
Conclusion:Whole body vibration improves the effectiveness of botulinum neurotoxin A injections in relieving tiptoe and improving the gross motor function of children with spastic diplegic cerebral palsy.
