Comprehensive treatment in stroke unit can improve the cognitive function and the life quality of stroke survivors with vascular cognitive impairment as well as the mental state of their caregivers
10.3760/cma.j.issn.0254-1424.2019.09.008
- VernacularTitle: 卒中单元综合治疗对血管性认知功能损害患者认知功能、生活质量以及照料者心理状态的影响
- Author:
Lijun LUO
1
;
Lijuan LI
;
Binling ZHOU
;
Yulan GOU
;
Junhua MEI
;
Jie YANG
;
Dongsheng WEI
Author Information
1. Department of Neurology, Wuhan No.1 Hospital, Wuhan 430022, China
- Publication Type:Clinical Trail
- Keywords:
Stroke;
Cognition;
Quality of life;
Caregivers;
Psychological status
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(9):674-679
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of comprehensive treatment in stroke unit on the cognition and life quality of patients with vascular cognitive impairment (VCI) and also its effects on the mental state of their caregivers.
Methods:Ninety-three persons with VCI were randomly divided into a control group (n=44) and a comprehensive treatment group (n=49) after being admitted into the stroke unit. Both groups took routine basic drugs (such as anti-platelet drugs, lipid lowering drugs, anti-hypertension drugs, huperzine-A tablets and Nicergoline tablets). The treatment group was additionally provided with limb movement rehabilitation training, social practice, cognitive training and health education. During the treatment, the treatment group′s caregivers were also given health education about VCI and stroke, systematic rehabilitation knowledge and skills training and appropriate anti-depressant and anxiety medication if need. Before the treatment, as well as 3 and 6 months after the treatment, the patients of both groups were evaluated using the mini-mental state examination (MMSE), the Montreal cognitive assessment (MoCA), their ability in the activities of daily living (ADL) was rated and Spitzer quality of life (QLI) values were assigned. The caregivers were evaluated using the Hamilton depression scale (HAMD) and the Hamilton anxiety scale (HAMA).
Results:After 3 and 6 months of treatment, the average MMSE, MoCA, ADL and QLI scores of the treatment group had improved significantly and were then significantly better than those of the control group at the same time points. The average HAMD score of the treatment group was also significantly better.
Conclusion:Comprehensive stroke unit therapy can improve the cognition and life quality of patients with vascular cognitive impairment. It can also improve the mental state of their caregivers.
