Transcranial magnetic stimulation for the treatment of non-fluent aphasia in stroke survivors
10.3760/cma.j.issn.0254-1424.2019.09.005
- VernacularTitle: 低频重复经颅磁刺激治疗脑卒中后亚急性期非流利性失语症的有效性及安全性评价
- Author:
Li WANG
1
;
Yi ZHU
1
;
Xiaodan LI
1
;
Xiuxiang WU
1
;
Yujie YANG
2
;
Meifang JI
1
;
Xiaojie MA
1
;
Jie HUANG
3
Author Information
1. The Second Affiliated Hospital of Hainan Medical College, Haikou 571300, China
2. Nanjing University of Chinese Medicine, Nanjing 210000, China
3. Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
- Publication Type:Clinical Trail
- Keywords:
Transcranial magnetic stimulation;
Stroke;
Aphasia;
Safety;
Effectiveness
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(9):662-667
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and effectiveness of repeated transcranial magnetic stimulation (rTMS) for treating non-fluent aphasia after stroke.
Methods:Forty-five stroke survivors with non-fluent aphasia were randomly divided into a 0.5 Hz group, a 1 Hz group and a sham group, each of 15. In addition to routine linguistic training, the three groups were given rTMS over the inferior frontal gyrus of the right hemisphere at the corresponding frequency or sham stimulation. Before as well as 5 and 10 days after the treatment, all of the subjects were evaluated using the Chinese version of the Western Aphasia Battery (WAB). The occurrence of adverse events was also observed.
Results:Before treatment, no significant differences were observed in the groups′ average aphasia ratio, spontaneous speech, listening comprehension, retelling and naming using the WAB. After 5 and 10 days significant increases were observed in the average WAB scores of all three groups, but the listening comprehension of the 0.5 Hz group was significantly better than that of the sham group 10 days later, as was the spontaneous speech of the 1 Hz group.
Conclusion:rTMS at either 1 Hz or 0.5 Hz can improve the linguistic functioning of stroke survivors with non-fluent aphasia. Both 0.5 Hz and 1 Hz rTMS are safe, but the latter is more effective.
