Application and advances in the research of animal models in burn research
10.3760/cma.j.issn.1009-2587.2019.09.009
- VernacularTitle: 动物模型在烧伤研究中的应用及研究进展
- Author:
Yongcun ZHANG
1
;
Liang WANG
;
Jin LU
;
Hao ZHOU
;
Hongtai TANG
Author Information
1. Burn Institute of PLA, Department of Burn Surgery, the First Affiliated Hospital, Naval Medical University, Shanghai 200433, China
- Publication Type:Review
- Keywords:
Burns;
Models, animal;
Cicatrix;
Escharectomy;
Tangential excision
- From:
Chinese Journal of Burns
2019;35(9):692-696
- CountryChina
- Language:Chinese
-
Abstract:
The occurrence, development, and prognosis of burn is a complicated pathophysiological process involving many organs and systems. With the development of science and technology and update of treatment concept, more and more new materials, new equipments, and new methods are applied to the diagnosis and treatment of burn. Animals similar to humans in anatomical structure and physiological function are the ideal models for research of burn. Nowadays, animal models of burn have been developed to simulate different aspects of burn. These models provide important essential support for elucidating the pathophysiological mechanism of burns and exploring new therapeutic interventions and materials for human beings. Understanding the advantages and limitations of these animal models is essential for the research of burn.
