Study on thyroid hormone levels and influence factors in drug users in a drug rehabilitation center in Jiangsu province
10.3760/cma.j.issn.0254-6450.2019.09.022
- VernacularTitle: 江苏省某戒毒所男性吸毒人员甲状腺激素水平及影响因素研究
- Author:
Lingyun ZHUO
1
;
Peng HUANG
;
Haozhi FAN
;
Jingjing WU
;
Yan WANG
;
Xiangyu YE
;
Rongbin YU
Author Information
1. School of Public Health, Nanjing Medical University, Nanjing 211166, China
- Publication Type:Journal Article
- Keywords:
Drug use;
Thyroid;
Hepatitis C virus;
Triiodothyronine
- From:
Chinese Journal of Epidemiology
2019;40(9):1134-1138
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the serum levels of thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), triiodothyronine (T3), and thyroxine (T4) and identify the related influencing factors of thyroid dysfunction in drug users.
Methods:From June to August 2018, a face-to-face questionnaire survey was conducted in 788 male drug users in a drug rehabilitation center in Jiangsu province to collect their socio-demographic information. Then, venous blood sample was collected from each participant for the detection of various hematological indicators, such as thyroid hormones.
Results:The abnormal rates of T3, T4, FT3, FT4 and TSH were 4.57%, 1.27%, 0.51%, 0.38% and 0.89%, respectively, in the male drug users. HCV infection was an influencing factor for abnormal T3 level in the male drug users (OR=8.52, 95%CI: 2.36-30.74, P=0.001). And serum T3 (P<0.001) and T4 (P=0.048) levels increased with increasing HCV viral load.
Conclusions:HCV infection was an influencing factor for the abnormality of serum T3 level in drug users. Therefore, thyroid-related knowledge should be added in the health education for drug users, and the monitoring of thyroid function should be strengthened for drug users infected with HCV.
