Therapeutic effect of anterior approach combined with liver hanging maneuver for right hepatectomy in patients with large hepatocellular carcinoma
10.3670.cma.j.issn.1007-631X.2019.00.012
- VernacularTitle: 前入路联合悬吊法切除右肝大肝癌的疗效分析
- Author:
Jun WU
1
;
Kai YIN
1
;
Jianwei XU
1
;
Lide TAO
2
;
Lihong ZHANG
2
Author Information
1. Department of Hepatobiliary Surgery, Taixing People′s Hospital of Yangzhou University, 225400, China
2. Department of Hepatobiliary Surgery, Affiliated Hospital of Yangzhou University, Jiangsu 225499, China
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Hepatectomy;
Outcome assessment
- From:
Chinese Journal of General Surgery
2019;34(9):787-790
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate hepatectomy by anterior approach combined with liver hanging maneuver against conventional right hepatectomy in patients with large hepatocellular carcinoma (HCC).
Methods:Of the 62 cases, 29 patients underwent anterior approach hepatectomy and 33 did conventional hepatectomy.
Results:The overall operative time (t=1.815, P=0.037) and parenchymal transsection time (t=4.591, P=0.000) were longer in the anterior approach group than in the conventional group. More cases got radical resection in the anterior group (χ2=7.280, P=0.007). Log-rank test showed that 1, 3 and 5-year overall survival rate (OS) in the anterior approach group and the conventional group was 86.1%, 50.1%, 32.6% vs 75.8%, 30.3%, 18.9%, respectively (χ2=5.24, P=0.022), 1, 3 and 5-year disease free survival rate (DFS) were 75.3%, 42.1%, 31.0% vs 66.1%, 24.4%, 10.1%, respectively (χ2=4.38, P=0.037), and recurrence rate were 23.6%, 49.5%, 64.8% vs 36.7%, 63.7%, 82.5%, respectively (χ2=5.61, P=0.018).
Conclusion:Long term survival of patients with large sized HCC undergoing hepatectomy through the anterior approach combined with liver hanging maneuver is better than that of conventional approach.