The Efficacy of Low Molecular Weight Heparin for the Prevention of Venous Thromboembolism after Hip Fracture Surgery in Korean Patients.
10.3349/ymj.2016.57.5.1209
- Author:
Kwang Kyoun KIM
1
;
Yougun WON
;
Ye Yeon WON
Author Information
1. Department of Orthopedic Surgery, Stanford University College of Medicine (Visiting professor), Stanford, CA, USA.
- Publication Type:Original Article
- Keywords:
Low molecular weight heparin;
deep vein thrombosis;
pulmonary embolism;
hip fracture
- MeSH:
Aged;
Anticoagulants/*therapeutic use;
Female;
Heparin, Low-Molecular-Weight/*therapeutic use;
Hip Fractures/classification/*surgery;
Humans;
Male;
Middle Aged;
Postoperative Complications/*prevention & control;
Pulmonary Embolism/etiology/*prevention & control;
Republic of Korea;
Venous Thromboembolism/*prevention & control;
Venous Thrombosis/etiology/*prevention & control
- From:Yonsei Medical Journal
2016;57(5):1209-1213
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The aim of this study was to investigate the efficacy of low-molecular-weight heparin (LMWH) for the prevention of venous thromboembolism in Korean patients who underwent hip fracture surgery (HFS). MATERIALS AND METHODS: Prospectively, a total 181 cases were classified into the LMWH user group (116 cases) and LMWH non-user group (65 cases). Each group was sub-classified according to fracture types as follows: 81 cases of intertrochanteric fracture (group A: 49, group B: 32) and 100 cases of neck fracture (group C: 67, group D: 33). We compared the incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) according to LMWH use. RESULTS: Of the 181 cases, four DVTs were found in the LMWH user groups (1 in group A, and 3 in group C). One case of PE was found in LMWH non-user group D. The incidences of DVT and PE showed no statistically significant differences between the LMWH user and non-user groups (p=0.298 and 0.359, respectively). In subgroup analysis, no statistically significant differences were found between groups A and B and between groups C and D. CONCLUSION: The administration of LMWH was not effective in the prevention of venous thromboembolism and PE in the Korean patients who underwent HFS.
