Retrospective study on the risk factors related to intraabdominal infection after anatomical hepatectomy
10.3760/cma.j.issn.1007-631X.2019.09.005
- VernacularTitle: 解剖性肝切除术后腹腔感染并发症分析
- Author:
Yali TIAN
1
;
Lian CHEN
1
;
Qing SUN
1
;
Xinlong CUI
1
;
Shiteng LIU
2
;
Liang MAO
2
;
Yudong QIU
2
;
Bingbing LI
1
Author Information
1. Department of Anesthesiology, Drum Tower Hospital, Nanjing University, Nanjing 210008, China
2. Department of General Surgery, Division of Hepatobiliary Pancreatic Surgery, Drum Tower Hospital Nanjing University, Nanjing 210008, China
- Publication Type:Journal Article
- Keywords:
Hepatectomy;
Fluid management;
Intraabdominal infection
- From:
Chinese Journal of General Surgery
2019;34(9):762-765
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the incidence and related risk factors of postoperative intraabdominal infection in patients undergoing anatomical hepatectomy.
Methods:The clinical data from 122 patients who underwent anatomical major hepatectomy in our institution were retrospectively analyzed. The electronic medical data were retrieved for further analysis including the amount of crystalloid and colloid fluid infused, intraoperative estimated blood loss, volume of blood transfusion, the dosage of vasoactive drugs, postoperative liver function, inflammation index, the incidence of intraabdominal infection and the length of hospital stay (LOS).
Results:Patients were divided into infection group (n=39) and non- infection group (n=83). Intraabdominal infection was correlated with preoperative cirrhosis, the elevated direct bilirubin and alanine aminotransferase, the duration of operation, bilioenteric anastomosis or cholangiotomy, the infusion volume of colloid and crystalloid fluid, transfusion volume, direct bilirubin level on the POD 1(post-operation on day 1) (P<0.05); Multivariate analysis showed the incidence of intraabdominal infection was highly correlated with the amount of intraoperative colloid fluid bilioenteric anastomosis(P<0.05).
Conclusions:Intraoperative infused volume of synthetic colloid, along with bilioenteric anastomosis are independent risk factors for postoperative intraabdominal infection.