Value of multi-parametric MRI in mammographically detected breast imaging reporting and data systems 3 to 4 exclusive microcalcifications
10.3760/cma.j.issn.1005-1201.2019.09.003
- VernacularTitle: 多参数MRI对X线摄影乳腺影像报告和数据系统3~4类单纯微钙化病变的诊断效能
- Author:
Changyu ZHOU
1
;
Xianliang ZHAO
;
Yangyang BU
;
Jiali ZHOU
;
Ping XIANG
;
Maosheng XU
Author Information
1. Department of Radiology, the First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China
- Publication Type:Journal Article
- Keywords:
Mammography;
Magnetic resonance imaging;
Microcalcifications
- From:
Chinese Journal of Radiology
2019;53(9):728-732
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the value of multi-parametric MRI in mammographically detected breast imaging reporting and data systems (BI-RADS) 3 to 4 exclusive microcalcifications.
Methods:A retrospective analysis was performed in 152 patients with mammographically detected BI-RADS 3 to 4 exclusive microcalcifications from January 2013 to December 2017. All patients underwent bilateral breast multi-parametric MRI before surgical biopsy. Microcalcifications were classified according to BI-RADS by two radiologists with more than 10 years′ experience in breast imaging. The area under the curve (AUC), sensitivity and specificity of BI-RADS 3 to 4 exclusive microcalcifications diagnosis by mammography and mammography plus MRI were calculated and compared using pathology as the gold standard.
Results:A total of 152 lesions (93 benign lesionsand 59 malignant lesions) were assessed in this study. The positive predictive value (PPV) of mammography for BI-RADS 3, 4A, 4B and 4C microcalcifications diagnosis were 22.2%(16/72), 5.0%(1/20), 48.5%(17/35) and 100.0%(25/25) respectively. The PPV of MRI for BI-RADS 2, 3, 4, 5 microcalcifications diagnosis were 1.6%(1/62), 7.1%(2/28), 72.2%(13/18) and 97.7%(43/44).The area under curve, sensitivity and specificity of mammography for BI-RADS 3 to 4 microcalcifications diagnosis were 0.676,72.9% and 60.2%. The area under curve, sensitivity and specificity of mammography plus MRI for BI-RADS 3 to 4 microcalcifications diagnosis were 0.982, 94.9% and 93.6%.
Conclusions:Multi-parametric MRI can improve the diagnostic accuracy in mammographically detected BI-RADS 3 to 4 exclusive microcalcifications, which is helpful to differentiate benign and malignant breast lesions with microcalcifications and avoid unnecessary biopsies.
