Research progress in mesenchymal stem cell-derived exosomes repairing skin tissues
10.3760/cma.j.issn.1001-8050.2019.09.016
- VernacularTitle: 间充质干细胞来源外泌体对皮肤组织修复作用的研究进展
- Author:
Yu LUO
1
;
Juan WANG
1
;
Youjian PENG
1
Author Information
1. Department of Stomatology, Renmin Hospital of Wuhan University, Wuhan 430060, China
- Publication Type:Review
- Keywords:
Mesenchymal stem cells;
Exosomes;
Skin wound repair
- From:
Chinese Journal of Trauma
2019;35(9):860-864
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells (MSCs) play an important role in skin wound repair because of their multi-directional differentiation potential, hematopoietic support and promotion of stem cell implantation, immune regulation and self-replication. Exosomes contain proteins and RNAs, which have anti-tumor immunity, angiogenesis promotion and other physiological functions. Different MSCs-derived exosomes have different mechanisms in the skin traumatic action. The author summarizes the research progress of different MSCs-derived exosomes in the field of skin tissue repair through elaborations on the traditional treatment methods for skin damage, the biological properties of exosomes, the mechanism of MSCs-derived exosomes in skin wound repair and in other diseases, providing reference for improving clinical repair.
