Therapeutic outcomes of high-dose intravenous steroids in the treatment of sight-threatening Graves′ ophthalmopathy

VernacularTitle: 大剂量激素冲击治疗对视力威胁型Graves眼病的治疗效果
Author: Mingshi HUANG ¹ ; Zhongyan SHAN ; Yushu LI
Author Information

1. Department of Endocrinology and Metablolism, China Medical University Affiliated the First Hospital, Insitude of Endocrinnology, Shenyang 110001, China
Publication Type:Journal Article
Keywords: Graves′ ophthalmopathy; Sight-threatening Graves′ ophthalmopathy; Dysthyroid optic neuropathy
From: Chinese Journal of Endocrinology and Metabolism 2019;35(9):784-788
CountryChina
Language:Chinese
Abstract: Graves′ ophthalmopathy is a complex autoimmune disease characterized by inflammation and the orbital connective/adipose tissue with infiltration. About 3% to 7% of patients with Graves′ ophthalmopathy can have severe or very severe course of disease. In severe forms of Graves′ ophthalmopathy, there might occur considerable exophthalmos complicated in some cases with corneal ulceration due to incomplete closure of the eyelids and (or) pressure on optic nerve leading to neuropathy (dysthyroid optic neuropathy). The patient′s visual acuity and the color perception decreased sharply , which seriously affected the patients quality of life. In this paper, we explore effective therapies by compared the effects of high-dose intravenous steroids for the treatment of sight-threatening Graves′ ophthalmopathy in 2 cases.