Relationship between metabolic syndrome and total bilirubin in nonagenarians and centenarians living in Hubei Zhongxiang Province
10.3760/cma.j.issn.1000-6699.2019.09.005
- VernacularTitle: 湖北钟祥长寿老人代谢综合征与血清总胆红素的相关性分析
- Author:
Guifen ZHANG
1
;
Hua WANG
1
;
Guangming YE
2
;
Yu DONG
1
;
Chunling TAN
1
Author Information
1. Department of Geriatric, Zhongnan Hospital, Wuhan University, Wuhan 430071, China
2. Department of Clinical Laboratory, Zhongnan Hospital, Wuhan University, Wuhan 430071, China
- Publication Type:Journal Article
- Keywords:
Elderly people;
Metabolic syndrome;
Total bilirubin
- From:
Chinese Journal of Endocrinology and Metabolism
2019;35(9):752-755
- CountryChina
- Language:Chinese
-
Abstract:
Metabolic syndrome is closely related to target organ injury such as heart, brain, and kidney. And bilirubin is an effective antioxidant. At present, there is a lack of research data on metabolic syndrome and serum total bilirubin in longevity elderly people. This study aimed to study the prevalence of the metabolic syndrome and its correlation with serum total bilirubin level in nonagenarians and centenarians living in Hubei Zhongxiang Province. According to the demographic information provided by Zhongxiang Civil Affairs Bureau, 128 elderly people were interviewed and 11 of them were excluded. A total of 117 population were included in the study. Questionnaires, physical examination, and blood test were made. 117 subjects aged 90-113 years with an average age of (98.6±4.8) years old were analysed. The prevalence of metabolic syndrome and its diagnostic components were obesity 19.7%, hyperglycemia 29.9%, hypertension 94.0%, hypertriglyceridemia 33.3%, low high density lipoprotein-cholesterol (HDL-C) levels 17.1%, and metabolic syndrome 23.9%. Logistic regression analysis found that the total bilirubin level was negatively correlated with metabolic syndrome and triglyceride levels(P<0.05), but not with obesity, hyperglycemia, hypertension, and total cholesterol (P>0.05). The nonagenarians and centenarians have a low prevalence of metabolic syndrome in Zhongxiang, Hubei Province, total bilirubin was negatively correlated with metabolic syndrome and triglyceride.
