A prospective study on the influence of metabolic syndrome on the risks of cardiovascular disease events and all-cause mortality for urban residents aged 40-79 years in Guiyang
10.3760/cma.j.issn.1000-6699.2019.09.003
- VernacularTitle: 贵阳市城区40～79岁代谢综合征人群发生心血管事件和各种死亡风险的前瞻性队列研究
- Author:
Hong LI
1
;
Lanrong LIU
2
;
Lixin SHI
;
Qiao ZHANG
;
Nianchun PENG
;
Ying HU
;
Na HAN
;
Yuxing YANG
Author Information
1. Department of Endocrinology and Metabolism, the Affiliated Hospital of Guiyang Medical University, Guiyang 550004, China
2. Department of Endocrinology and Metabolism, the Affiliated Hospital of Guiyang Medical University, Guiyang 550004, China (Liu Lanrong is working on the Department of Endocrinology, People′s Hospital of Chengwu County, Heze 274200, China)
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome;
Cardiovascular disease events;
All-cause mortality;
Cohort study
- From:
Chinese Journal of Endocrinology and Metabolism
2019;35(9):743-746
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influence of metabolic syndrome on the risks of cardiovascular disease (CVD) events and all-cause mortality.
Methods:In this prospective cohort study, urban residents aged 40-79 years in Guiyang were followed-up for three years. The end-points were CVD events and all-cause mortality. COX proportional hazards model were used for the corresponding hazard ratios (HRs) of CVD events and all-cause mortality. Metabolic syndrome was defined according to the 2005 International Diabetes Federation (IDF) criteria.
Results:A total of 7 313 subjects were included. 146 cases of CVD events and 80 cases of all-cause mortality were recorded. After adjusting for gender, age, smoking, alcohol consumption, and blood lipid levels, the metabolic syndrome increased the risks of CVD events and all-cause mortality. The HRs were 1.43 (P=0.037) and 1.25 (P=0.418), respectively. As compared metabolic syndrome with non-metabolic syndrome, an increased risk of CVD events was found. The HR was 1.43 (P=0.013). No significantly increased risk of all-cause mortality was found in subjects with metabolic syndrome.
Conclusion:The metabolic syndrome was associated with increased risk of CVD events and there was no significant increase in all-cause mortality. Metabolic syndrome is an important risk factor for CVD events.
