Four Cases of HNPCC Including Two Cases with Synchronous Stomach Cancer.
- Author:
Seon Ja PARK
1
;
Yeon Soon JUNG
;
Seong Hoon CHANG
;
Ho Sung SON
;
Byoung Kun LEE
;
Moo In PARK
;
Byung Kwon AHN
;
Sung Uhn BAEK
;
Ja Young KOO
Author Information
1. Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea.
- Publication Type:Case Report
- Keywords:
HNPCC;
Gastric cancer
- MeSH:
Colorectal Neoplasms;
Humans;
Pedigree;
Primary Prevention;
Stomach Neoplasms*;
Stomach*
- From:Journal of the Korean Society of Coloproctology
2000;16(5):339-345
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by early manifestation of colorectal cancer (CRC), occurrence of multiple colorectal tumors and high frequencies of extracolonic malignancies. Evaluation of clinical findings in concert with a well-documented and extended pedigree and genetic studies of colorectal cancer can identify person who are at high risk and who thereby might benefit from targeted early detection and primary prevention programs. Here we report 4 cases of HNPCC including 2 cases with synchronous gastric cancers.
