Intravenous thrombolytic therapy for wake-up stroke under the guidance of neuroimaging
10.3760/cma.j.issn.1673-4165.2019.10.007
- VernacularTitle: 神经影像学指导下醒后卒中的静脉溶栓治疗
- Author:
Kehang XIE
1
;
Wu ZHOU
Author Information
1. Department of Neurology, Zhuhai Integrated Traditional Chinese and Western Medicine Hospital, Zhuhai 519020, China
- Publication Type:Review
- Keywords:
Stroke;
Brain ischemia;
Time factor;
Thrombolytic therapy;
Tomography, X-ray computed;
Magnetic resonance imaging;
Magnetic resonance angiography;
Perfusion imaging;
Cerebral angiography
- From:
International Journal of Cerebrovascular Diseases
2019;27(10):755-759
- CountryChina
- Language:Chinese
-
Abstract:
About a quarter of acute ischemic strokes are wake-up strokes. Due to the uncertainty of the onset time, patients with wake-up stroke were considered to be unable to receive intravenous thrombolysis. Although the current guidelines recommend that the time window for intravenous thrombolytic therapy is 4.5 h, recent studies have shown that intravenous thrombolytic therapy is safe and effective for patients with wake-up stroke after neuroimaging screening. This article reviews the recent research progress on intravenous thrombolytic therapy for wake-up stroke under the guidance of neuroimaging in order to provide a reference for clinical practice.