Relationship between modified Frailty Index and development of delirium after artificial joint replacement in elderly patients
10.3760/cma.j.issn.0254-1416.2019.10.003
- VernacularTitle: 修正衰弱指数与人工关节置换术后老年病人谵妄发生的关系
- Author:
Fan CUI
1
;
Wei ZHAO
2
;
Chunjing LI
1
;
Dongliang MU
1
Author Information
1. Department of Anesthesiology and Surgical Intensive Care, Peking University First Hospital, Beijing 100034, China
2. Department of Anesthesiology, The Forth Hospital of Hebei Medical University, Shijiazhuang 050011, China
- Publication Type:Journal Article
- Keywords:
Arthroplasty, replacement;
Aged;
Delirium;
Modified frailty index
- From:
Chinese Journal of Anesthesiology
2019;39(10):1158-1161
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship between modified Frailty Index (mFI) and development of delirium after artificial joint replacement in elderly patients.
Methods:Elderly patients (aged ≥60 yr) who scheduled for elective hip or knee replacement, were enrolled.Preoperative frailty was assessed using the mFI scale.All the patients received surgery under combined spinal-epidural anesthesia.Primary outcome was the incidence of delirium within 5 days after operation, and delirium was assessed by Confusion Assessment Method or Confusion Assessment Method-Intensive Care Unit.The patients were divided into delirium group and non-delirium group according to whether delirium occurred or not.
Results:A total of 620 patients were included in the study, the mFI was 0.09 (0.18), and the incidence of delirium within 5 days after surgery was 8.5%.The results of multivariate logistic regression analyses showed that increase in age (OR 1.068, 95% CI 1.018-1.120, P=0.007), higher postoperative consumption of morphine (OR 1.089, 95% CI 1.051-1.128, P<0.01) and higher mFI (OR 2.465, 95% CI 1.636-3.714, P<0.01) were the independent risk factors for postoperative delirium.
Conclusion:Higher mFI is the independent risk factor for delirium after artificial joint replacement in elderly patients.
