The changes of transcranial sonography in end-stage renal disease with restless legs syndrome
10.3760/cma.j.issn.1004-4477.2019.10.006
- VernacularTitle: 终末期肾脏病伴不宁腿综合征患者的经颅超声改变
- Author:
Caishan WANG
1
;
Jing LUO
1
;
Hui LI
1
;
Yujing SHENG
1
;
Ying ZHANG
1
;
Zhoubing ZHAN
2
;
Yingchun ZHANG
1
Author Information
1. Department of Ultrasound, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
2. Department of Nephrology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
- Publication Type:Clinical Trail
- Keywords:
Ultrasonography, Doppler, transcranial;
Substantia nigra;
Brainstem raphe;
Red nucleus
- From:
Chinese Journal of Ultrasonography
2019;28(10):859-863
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the neuroimaging characteristics of transcranial ultrasound in end-stage renal disease (ESRD) with restless legs syndrome.
Methods:Transcranial sonography (TCS) was performed in ESRD with restless legs syndrome (RLS+ group, n=41), ESRD without restless legs syndrome (RLS- group, n=57) and control group (n=47), who were enrolled in the Second Affiliated Hospital of Soochow University from January 2017 to December 2018. The differences of the neuroimaging characteristics of TCS in substantia nigra (SN), brainstem raphe (BR) and red nucleus(RN) among the three groups were analyzed.
Results:The rate of SN hypoechogenicity was significantly higher in RLS+ group (36.6%, 15/41) than that in RLS- group (19.3%, 11/57) and control group(8.5%, 4/47) (χ2=10.6, P<0.05). The rate of abnormal BR echogenicity was significantly higher in RLS+ group (34.1%, 14/41) and RLS- group (29.8%, 17/57) than that in control group(10.6%, 5/47) (χ2=7.7, P<0.05). The rate of RN hyperechogenicity was significantly higher in RLS+ group (51.2%, 21/41) than that in RLS- group (21.1%, 12/57) and control group (10.6%, 5/47) (χ2=19.8, P<0.05). Between RLS+ and RLS- groups, when SN, BR and RN were all of positive performance, the accuracy of diagnosing RLS+ reached 70% (7/10).
Conclusions:The echogenicity changes of SN, BR and RN on TCS could provide valuable neuroimaging information for the clinical diagnosis and treatment of ESRD with restless legs syndrome.
