Research progress on microRNA and miRNA-CNVs congenital heart defects
10.3760/cma.j.issn.1001-4497.2019.10.013
- VernacularTitle: MicroRNA及与拷贝数变异相关的microRNA在先天性心脏病中的研究进展
- Author:
Yuan TIAN
1
;
Yanxiao LIANG
2
;
Hong PANG
1
Author Information
1. Department of Medical Genetics, Shenyang Children's and Women's Hospital, Shenyang 110000, China
2. Department of Cardiac Surgery, Shengjing Hospital of China Medical University, Shenyang 110003, China
- Publication Type:Review
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2019;35(10):636-640
- CountryChina
- Language:Chinese
-
Abstract:
Congenital heart defects(CHD) are the most common birth defects in China. However, the etiology of most CHD remains unclear. In recent years, with the development of molecular diagnostic techniques, some researchers began to pay attention to microRNA in CNVs detected in CHD children. However, microRNA in CNVs(miRNA-CNVs) as a genetic mechanism in CHD is not known with certainty. So the research progress of the relationship between microRNA, CNVs, miRNA-CNVs and CHD were summarized in this paper.
