The research focus on short- and long-term postoperative prognosis of acute type A aortic dissection patient complicated with renal malperfusion
- VernacularTitle: 急性A型主动脉夹层合并术前肾灌注不良患者术后近、远期预后
- Author:
Honglei ZHAO
1
;
Sichong QIAN
1
;
Kai ZHANG
1
;
Hong LIU
1
;
Xudong PAN
1
;
Tao BAI
1
;
Jun ZHENG
1
;
Yongming LIU
1
;
Junming ZHU
1
;
Lizhong SUN
1
Author Information
- Publication Type:Journal Article
- Keywords: Acute type A aortic dissection; Renal malperfusion; Mortality; Acute renal failure
- From: Chinese Journal of Thoracic and Cardiovascular Surgery 2019;35(10):593-597
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To find out what the exact impact of renal malperfusion on short- and long-term postoperative prognosis of ATAAD patietns.
Methods:218 patients with ATAAD undergoing surgical repair from June 2009 to May 2012 . Mean age was(47.8±10.7) years and 170 were male(78.0%). Based on computed tomographic angiography and laboratory test, 48 patients were diagnosed with preoperative renal malperfusion(22.0%). Clinical data were compared between two groups and risk factors for short- and long-term mortality identified using Cox regression.
Results:Patients with renal malperfusion showed significantly higher incidences of short-term mortality(22.9% vs 8.3%,P =0.023), long-term mortality(87.0% vs 72.9%,P =0.003) and postoperative acute kidney failure(20.8% vs 4.1%,P <0.001). Renal malperfusion was the risk factor for short-term mortality(OR 2.92, 95%CI 1.31-6.63,P =0.009) and long-term mortality(OR 2.56, 95%CI 1.32-4.94,P =0.005).
Conclusion:Renal malperfusion significantly increases the postoperative risk of short-term mortality, long-term mortality and incidence of postoperative acute renal failure in patients with ATAAD.
